鸡鼻相关淋巴组织中免疫细胞的定位分布

doi:10.11843/j.issn.0366-6964.2014.03.019

Abstract

Abstract:

The aim of this study was to explore the immune state of nasal-associated lymphoid tissue（NALT）in chicken.Nasal tissues were taken from 21-day-old Hailan White chicks to investigate the localization and the relative quantities of different immune cells by immunohistochemistry method.The results showed that NALT in chicken was mainly located in the mucosa of nasolacrimal duct，posterior nasal apertures and conchae nasals.NALT in the mucosa of nasolacrimal duct was the most developed.CD3⁺ and CD4⁺ T lymphocytes mainly distributed at the bottom of lamina propria under epithelium in NALT，which were found predominantly at the middle and inferior part of lamina propria.The number of CD8⁺ lymphocytes was low，and they scattered in middle part of NALT.Bu-1⁺ lymphocytes constituted the main population in NALT，and they distributed around the peripheral NALT densely and widely.Bu-1⁺ cells occupied the middle and inferior part overwhelmingly.The main antibody producing cells were IgA⁺ or IgM⁺ cells，and they scattered in the middle part of NALT predominantly.Ma⁺ cells mainly distributed in the deep loose connective tissue.MHC-Ⅱ⁺ cells distributed densely throughout the NALT.The number of MHC-Ⅱ⁺ cells was highest among the immune cells in NALT.The results demonstrated that there were several kinds of immune cells in NALT of chicken.These immune cells played an important role in immune defence at the upper respiratory tract.

CLC Number:

S852.4

YANG Shu-bao，ZHANG Ying-nan，MA Xin，YANG Li-hua，YAO Ji-yuan，QIAN Ai-dong,LUAN Wei-min. Localization of Immune Cells in Chicken Nasal-associate Lymphoid Tissues[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2014, 45(3): 477-482.

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Localization of Immune Cells in Chicken Nasal-associate Lymphoid Tissues

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